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- ArticleCourrière P, Paubel JP, Nivière P.C R Seances Soc Biol Fil. 1977;171(4):979-82.In this study, the authors propose a comparison between conformational properties and pharmacological activity of a series of adrenergic phenethylamines; in particular they conclude that if the alpha adrenergic compounds adopt a gauche conformation, beta adrenergics prefer a trans form.